Could You Be in Perimenopause and Not Know It?
Heather Watters FNP FMACP • November 2, 2025

November 2, 2025

Is It Perimenopause? How to Spot the Signs


Many people assume that perimenopause only begins when periods stop or hot flashes arrive. But the truth is more subtle: you might already be in perimenopause, even if your periods are still pretty regular or your symptoms feel vague. Recognizing this transition early gives you a chance to respond proactively rather than react after things feel too chaotic.

Let’s walk through how perimenopause often hides in plain sight, which signs to watch for, and what steps you can take now.


What Is Perimenopause?

Perimenopause is the transitional phase leading up to menopause. It begins when the ovaries gradually reduce their production of hormones, especially estrogen and progesterone, but has not yet reached the point where you’ve gone 12 full months without a period.

Because hormone levels fluctuate wildly during this time (rather than steadily decline), symptoms can come and go. Some months feel “normal,” others bring surprises.

Perimenopause can last several years (often 4–8 years) before menopause truly begins.


Why It’s Easy to Miss It

●    Symptoms overlap with other life stressors. Fatigue, mood shifts, brain fog, changes in sleep, these are things many of us attribute to burnout, parenting, or aging rather than hormones.

●    Periods can continue. Many people in perimenopause still menstruate regularly (though sometimes with subtle changes in flow or timing).

●    Hormones are erratic. A single blood test may look “normal” because hormone levels fluctuate day to day, even hour to hour.

●    Cultural conditioning. We tend to reserve the idea of “menopause” for later years; earlier hormonal changes often go unnamed or invalidated.

Because the signs are often dismissed or misattributed, many people live in perimenopause for years without recognizing what’s really happening.


Common (and Less Common) Signs of Perimenopause

Here are red flags that may point toward perimenopause, even if you’ve not connected them to hormones yet:

Frequent or classic symptoms:

●    Changes in menstrual cycles (shorter cycles, heavier or lighter flow, spotting)

●    Hot flashes and night sweats (vasomotor symptoms)

●    Sleep disruptions (difficulty falling asleep, waking at night)

●    Mood swings, irritability, anxiety, low mood

●    Vaginal dryness, urinary symptoms, low libido

●    Cognitive changes: memory lapses, trouble focusing (“brain fog”)

“Low-key” or surprising symptoms:

●    New sensitivity to skin, changes in hair or nails

●    Digestive shifts (e.g., bloating, gas)

●    Weight gain (especially central or belly fat)

●    Joint aches, muscle tension

●    Fatigue that doesn’t improve with rest

●    Shifts in cholesterol, blood sugar, or metabolic markers

The key is this: if multiple symptoms appear together, especially across mood, cycles, sleep, and cognition, the odds increase that hormones are involved.


Functional Testing: What to Explore

Because hormone levels fluctuate in perimenopause, smart, dynamic testing is often more helpful than a single blood draw. Here are some tests your functional/integrative practitioner may order:

  1. Comprehensive Hormone Panels These may include saliva or dried urine (such as the DUTCH test) to capture metabolite fluctuations over time. Some providers may order serial serum hormone tests (measuring estradiol, progesterone, FSH, LH at different cycle days). A single test often isn’t enough.
  2. Metabolic & Lipid Panels Estrogen plays a role in fat distribution, lipid profiles, and insulin sensitivity. Checking glucose, HbA1c, lipids, and fasting insulin may give insight into shifts happening with hormonal transition.
  3. Thyroid & Adrenal Testing Hormonal transitions often overlap with thyroid or adrenal stress. A complete thyroid panel, including TSH, free T4, free T3, and reverse T3, plus cortisol rhythm tests, can provide valuable context.
  4. Micronutrient and Inflammation Markers Deficiencies in vitamin D, magnesium, and B vitamins, as well as elevated inflammation markers (such as CRP and cytokines), can worsen perimenopausal symptoms.
  5. Optional: Gut / Microbiome or Detox Panels Hormones are processed through detox and elimination pathways, so assessing gut health or detox burden may help fine-tune your care plan.
  6. Symptom Tracking Over Time Tools like the Menopause Rating Scale help track changes over months and can guide more targeted support.

Why Addressing It Early Matters

If left unchecked, perimenopause can:


●    Worsen sleep, mood, and energy

●    Contribute to bone loss or metabolic imbalance

●    Increase cardiovascular risk

●    Accelerate symptoms like vaginal dryness

●    Reduce quality of life and disrupt daily functioning

What You Can Do Right Now (Even Without Testing)

You don’t need to wait for labs to start supportive actions:


●    Track your symptoms: note cycles, sleep, mood, and energy changes.

●    Clean up your diet and support gut health with whole, anti-inflammatory foods.

●    Build consistency in sleep, stress management, and gentle movement.

●    Prioritize nutrients like magnesium, omega-3 fats, B vitamins, and vitamin D.

●    Consider seeing a practitioner experienced in hormonal transitions and functional medicine.

Even if you’re not sure perimenopause is happening, these steps build hormonal resilience and can ease many midlife shifts.

Perimenopause isn’t a mysterious transition reserved for “older” women, it can begin earlier and manifest subtly. The more you understand your body’s patterns, symptoms, and shifts, the more power you have to navigate this change intentionally.

If in doubt, talk with a practitioner who specializes in hormones and functional testing to guide your plan. We can help!

References

  1. Santoro, N., et al. (2016). Perimenopause: From Research to Practice. PMC.
  2. Cunningham, A. C., et al. (2025). Perimenopause Symptoms, Severity, and Healthcare Implications. Nature Review.
  3. Crandall, C. J., Mehta, J., & Manson, J. E. (2023). Management of Menopausal Symptoms: A Review. JAMA.
  4. Metcalf, C. A., et al. (2023). Cognitive Problems in Perimenopause: A Review. PMC.
  5. Harvard Health Publishing. (n.d.). Perimenopause: Rocky Road to Menopause. Harvard Health.
  6. Rupa Health. (n.d.). A Functional Medicine Menopause Protocol: Comprehensive Testing, Nutrition, and Supplements. Rupa Health.


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